Research shows that GLP medications lower systemic inflammation independent of weight loss. Your systemic inflammatory marker, CRP, drops. Inflammatory cytokines drop. This matters because chronic inflammation is the root driver of nearly every age-related disease. See below for further research based articles.
The SELECT trial showed a 20% reduction in heart attacks, strokes, and cardivascular death in people without diabetes. And cardiovascular disease is still the #1 killer in America
The STEP-HFpEF trial showed major improvements in heart failure symptoms.
The FLOW trial showed a 24% reduction in kidney disease progression
Knee osteoarthritis pain dropped dramatically in the STEP 9 trial, far beyond what wieght loss alone would predict.
The SURMOUNT-OSA trial showed tirzepatide cut sleep apnea events by up to 63%. That is a results no CPAP machine can match. Better sleep then leads to better metaoblism, mood, and cognition
The EPIC_Norfolk study of ~10,000 adults found that A1C predicted death across the entire range, not just in diabetes. Glycemic control is a longevity lever.
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EQ Wellness
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